内容摘要：Morning light resets the rhythm. By evening, levels of a hormone called melatonin begin to surge, triggering drowsiness. Too much light in the evening — that extra hour from daylight saving time — delays that surge and the cycle gets out of sync.

Morning light resets the rhythm. By evening, levels of a hormone called melatonin begin to surge, triggering drowsiness. Too much light in the evening — that extra hour from daylight saving time — delays that surge and the cycle gets out of sync.

The Associated Press Health and Science Department receives support from the Howard Hughes Medical Institute’s Science and Educational Media Group. The AP is solely responsible for all content.LOUISVILLE, Ky. (AP) — The calls and emails started coming into

soon after doctors began experimenting with pig organs in humans.People worried they’ll never get a scarce human transplant asked: When could weAlex Berrios of Louisville, Kentucky, needs a second transplant but finding another human match is proving impossible. So he’s closely watching for a chance at pig kidney research.

Alex Berrios walks into his dialysis session in Louisville, Ky., on Oct. 4, 2024. (AP Photo/Shelby Lum)Alex Berrios walks into his dialysis session in Louisville, Ky., on Oct. 4, 2024. (AP Photo/Shelby Lum)

“It may not work, and I have to be OK with that,” Berrios said. “I think it’s worth the shot.”

Now two U.S. companies aim to begin the world’s first clinical trials of xenotransplantation in 2025 –of a larger problem permeating health care.

used in medical decisions — treatment guidelines, diagnostic tests, risk calculators — adjust the answers according to race or ethnicity in a way that puts people of color at disadvantage.Given how embedded these equations are in medical software and electronic records, even doctors may not realize how widely they impact care decisions.

“Health equity scholars have been raising alarm bells about the way race has been misused in clinical algorithms for decades,” said Dr. Michelle Morse, New York City’s chief medical officer.Change is beginning, slowly. No longer are obstetricians supposed to include race in determining the risk of a pregnant woman attempting vaginal birth after a prior C-section. The American Heart Association just removed race from a commonly used calculator of people’s heart disease risk. The American Thoracic Society has urged replacing race-based lung function evaluation.