内容摘要：. "You can love this dress. You can hate this dress. You can make whatever arguments you want about the ethics of this dress, Lululemon as a company, I really don't care, but it's not a thneed."

. "You can love this dress. You can hate this dress. You can make whatever arguments you want about the ethics of this dress, Lululemon as a company, I really don't care, but it's not a thneed."

I always recommend setting aside a day to check out a nearby island, especially if it's accessible by ferry.First-time visitors to the Caribbean may be surprised to find that, for the most part, life seems to move slower on the islands.

Be sure to leave time between activities or meals and embrace flexibility. If you have activities planned, I recommend doing one activity per day or setting aside at least half a day for each excursion.In Barbados, for example, I hired a driver to check out Bathsheba, a stunning rocky beach on Barbados' east coast. On our way back, my tour guide recommended stopping by a popular beachside restaurant, which wasn't on the itinerary.I ended up staying for a few hours, ordering food and drinks, and walking along the beach. I would have missed this delicious detour if I had been on a tight schedule, and I always advise embracing the slower island pace for the best experience.

Part of the joy of traveling is experiencing new cuisine, and the Caribbean offers a variety of food that reflects each island's history and culture.In Puerto Rico, I made it a point to eat mofongo, an African-influenced dish made from fried plantain. In

, I tried oil down, a delicious meat and vegetable stew.

On a girls' trip to Curaçao, we stopped by a local restaurant that had come highly recommended for its goat burgers. I was apprehensive at first, but it was one of the most delicious and memorable meals on the trip.Scientists already knew that semaglutide lowers blood sugar by acting directly on the pancreas. But when it comes to weight loss, the brain plays the main role. Even though

doesn’t easily cross the blood-brain barrier, it collects in certain brain regions that don’t have one—especially an area called the dorsal vagal complex, or DVC.This part of the brainstem includes two key areas: the area postrema and the nucleus of the solitary tract. Both are known to influence appetite, digestion, and metabolism. When semaglutide reaches this region, it activates brain cells that reduce hunger and body weight. But the details of that process have remained unclear—until now.

To better understand which brain cells were responsible for semaglutide’s effects, researchers at the Sahlgrenska Academy tracked how the drug affected mice. After semaglutide was injected, they looked for brain cells that became active. They found that many of these cells in the area postrema and the nucleus of the solitary tract expressed a gene called. This gene produces a neuropeptide called PACAP (pituitary adenylate cyclase-activating polypeptide), which is known to influence appetite and metabolism.